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of bacteria (Arias & Murray, 2009). Chapter 17 in this
text addresses the role of drug companies in creating
this overuse crisis.
Misuse caught the public’s attention with the publication
of the first IOM report on patient safety (Kohn et al.,
2000), which examined the high rate of medical errors in
hospitals, noting, as pointed out earlier, that thousands
of patients die every year from preventable adverse
events and another million are injured. Chassin’s (1997)
definition of misuse focuses on errors related to the
delivery of medical care, rather than the mis-application
of medical care without untoward consequences.
One recent estimate suggested that at least 250,000
people die each year from medical errors in hospital
settings; in 2016, medical errors were the third leading
cause of death in the U.S. (Makary & Daniel, 2016). The
cost of medical errors for 2008 was estimated to be
$17.1 billion(Van Den Bos et al., 2011).
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