The Unconscious States
Awareness of self and the environment: internal / external (difficulties)
(lack of response to painful stimulus)
clinical definitions of:
• coma (Glasgow Coma Scale) (induced coma)
• persistent vegetative state (PVS)
• traumatic head injury
• brain hypoxia
• epileptic seizure
• syncope
• other unconscious states (ex. Locked-in syndrome)
CONSCIOUSNESS:
Awareness of self and the environment: internal / external
(difficulties; how to measure?)
UNCONSCIOUSNESS:
Lack of response to painful stimulus
Coma (Glasgow Coma Scale) (induced coma)
persistent (permanent) vegetative state (PVS)
VS MCS
MAGNETIC RESONANCE IMAGING (MRI)
Traumatic Brain Injury (TBI)
• complex injury
• broad spectrum of symptoms
• and disabilities
Mayo Clinic: TraumaticBrainInjury.com
TBI
mild
severe
~ 30 min.
Brain Hypoxia (anoxia)
3 PAIRS OF ARTERIES TO THE HEAD:
• 1 PAIR VERTEBRAL
• 2 PAIRS CAROTID
Epileptic Seizure (epileptic fit)
Neuronal activity:
• Abnormal
• Excessive
• Generalized
• Synchronous
Electro-EncephaloGram (EEG)
Syncope (fainting):
• Temporary loss of consciousness
• Sudden drop in blood pressure
Other unconscious states:
• Non-epileptic seizure
• Locked-in syndrome
• Etc.
LOCKED-IN SYNDROME:
• Aware
• cannot move or communicate verbally
• complete paralysis of nearly all voluntary muscles
• Except for vertical eye movements and blinking
Damage to specific portions of the lower brain
and brainstem, with no damage to the upper
brain (cerebral cortex).
MAGNETIC RESONANCE IMAGING (MRI)
POSITRON EMISSION TOMOGRAPHY (PET)
COMPUTED TOMOGRAPHY (CT)
VEGETATIVE
STATE
MINIMALLY
CONSCIOUS
STATE
LOCKED-IN
SYNDROME
(MRI)
DIAGNOSIS -> PROGNOSIS
MANAGEMENT, RELIEF: PAIN / SUFFERING
BIOETHICAL ANALYSIS: BENEFIT / BURDEN
BIOETHICAL MEANS OF LIFE SUPPORT:
• ORDINARY (PROPORTIONATE) / EXTRAORDINARY (DISPROPORTIONATE)
CLINICAL MEANS OF LIFE SUPPORT:
• STANDARD MEDICAL PRACTICE / EXPERIMENTAL TREATMENT
ETHICAL OBLIGATION RE. VITAL ORGANS: ASSIST / SUBSTITUTE
WHEN TO WITHHOLD OR WITHDRAW LIFE SAVING TREATMENT?
ERD
32. While every person is obliged to use
ordinary means to preserve his or her health,
no
person should be obliged to submit to a health
care procedure that the person has judged,
with a free and informed conscience, not to
provide a reasonable hope of benefit without
imposing excessive risks and burdens on the
patient or excessive expense to family or
community.
33. The well-being of the whole person must
be taken into account in deciding about any
therapeutic intervention or use of technology.
Therapeutic procedures that are likely to
cause harm or undesirable side-effects can be
justified only by a proportionate benefit to
the patient
56. A person has a moral obligation to use
ordinary or proportionate means of preserving
his or her life. Proportionate means are those
that in the judgment of the patient offer a
reasonable hope of benefit and do not entail
an excessive burden or impose excessive
expense on the family or the community.
57. A person may forgo extraordinary or
disproportionate means of preserving life.
Disproportionate means are those that in the
patient’s judgment do not offer a reasonable
hope of benefit or entail an excessive burden,
or impose excessive expense on the family
or the community.
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